OKAMOTO Keiichiro, Ph.D. (Associate Professor, Division of Oral Physiology, Faculty of Dentistry, Graduate School of Medical and Dental Sciences; Cooperating Faculty Member of Sakeology Center) and KAKIHARA Yoshito, Ph.D. (Assistant Professor, Division of Dental Pharmacology, Faculty of Dentistry, Graduate School of Medical and Dental Sciences; Faculty Member of Sakeology Center), in Industry-government-academia collaboration with Hakkaisan Brewery Co., Ltd. (Minamiuonuma, Niigata) and Food Research Center, Niigata Agricultural Research Institute (Kamo, Niigata) (Niigata University; PI: KAKIHARA Yoshito, Ph.D.), have elucidated that Rice-koji extracts reduce anxiety- and pain-responses caused by physical stress using animal models and cultured cell models.
The research result was published in “Nutrients.”

[Paper Information]
【Journal】Nutrients 2023, 15(18), 3989
【Title of the paper】Preventive roles of Rice-koji extracts and ergothioneine on anxiety- and pain-like responses under psychophysical stress conditions in male mice
【Authors】Kajita Piriyaprasath, Yoshito Kakihara, Atsushi Kurahashi, Mayumi Taiyoji, Kazuya Kodaira, Kotaro Aihara, Mana Hasegawa, Kensuke Yamamura, Keiichiro Okamoto*
*Author to whom correspondence should be addressed
【doi】10.3390/nu15183989

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